|T000069, MKNK1 Tracer (PBI 7344)
Compound Image

T000069

MKNK1 Tracer (PBI 7344)

  • Description

    Formula:

    C61H68BF4N9O11

    avg. MolWt:

    1190.07 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm

    clogP:

    8.03
  • References

    Contributing Lab:

    Promega Corp., Madison

  • Experimental

    Assay window 2.1
    \(Z'\) 0.57
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    341 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Foretinib

    \(\mathrm{EC}_{50}\):

    137 nM
    displacement curve
    raw data

    Comment: NLuc-MKNK1