|T000065, K14 Tracer
Compound Image

T000065

K14 Tracer

  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm
  • References

    Contributing Lab:

    Promega Corp., Madison and Knapp Lab, Knapp Lab, University of Frankfurt

  • Experimental

    Assay window 9.1
    \(Z'\) 0.95
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    2457 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Vactosertib

    \(\mathrm{EC}_{50}\):

    267 nM
    displacement curve
    raw data

    Comment: ACVR1B/ALK4-NLuc

    Reference: PMID

    Assay window 8.4
    \(Z'\) 0.96
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    1523 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Vactosertib

    \(\mathrm{EC}_{50}\):

    367 nM
    displacement curve
    raw data

    Comment: TGFβR1/ALK5-NLuc

    Reference: PMID