|T000051, XAC Tracer G-1 (CS315402)
Compound Image

T000051

XAC Tracer G-1 (CS315402)

  • Description

    Formula:

    C50H56BF2N11O8

    avg. MolWt:

    987.87 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm

    clogP:

    3.85
  • References

    Contributing Lab:

    Promega Corp., Madison

    Vendor:

    Promega
  • Experimental

    Assay window 7.9
    \(Z'\) 0.79
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    101 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    XAC

    \(\mathrm{EC}_{50}\):

    158 nM
    displacement curve
    raw data

    Comment: HiBiT-ADORA1

    Assay window 8.1
    \(Z'\) 0.97
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    607 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    XAC

    \(\mathrm{EC}_{50}\):

    146 nM
    displacement curve
    raw data

    Comment: HiBiT-ADORA2A

    Assay window 6.0
    \(Z'\) 0.67
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    22 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    XAC

    \(\mathrm{EC}_{50}\):

    137 nM
    displacement curve
    raw data

    Comment: HiBiT-ADORA2B

    Assay window 7.0
    \(Z'\) 0.87
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    95 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    XAC

    \(\mathrm{EC}_{50}\):

    412 nM
    displacement curve
    raw data

    Comment: HiBiT-ADORA3