|T000021, HSP90 Tracer (CS1810C569)
Compound Image

T000021

HSP90 Tracer (CS1810C569)

  • Description

    Formula:

    C31H27BF2IN9O3S

    avg. MolWt:

    781.4 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm

    clogP:

    4.81
  • References

    Contributing Lab:

    Promega Corp., Madison

    Vendor:

    Promega
  • Experimental

    Assay window 3.84
    \(Z'\) 0.88
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}^{\,\mathrm{app}}\):

    129 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled parent ligand

    \(\mathrm{EC}_{50}\):

    162 nM
    displacement curve
    raw data

    Comment: NLuc-HSP90AB1